Microwave Assisted Organic Synthesis [reprint 2005]

Tierney Jason. (ed.) Microwave Assisted Organic Synthesis [reprint 2005] 2007 [pdf 292sc 280c. 7.37mb] 

The first reports on the application of microwaves in organic synthesis date back to 1986, but it was not until the recent introduction of specifically designed and constructed equipment, which countered the safety and reproducibility concerns, that synthetic application of microwaves has become established as a laboratory technique. Microwave assisted synthesis is now being adopted in many industrial and academic laboratories to take advantage of the novel chemistry that can be carried out using a variety of organic reaction types.

This book demonstrates the underlying principles of microwave dielectric heating and, by reference to a range of organic reaction types, it's effective use in synthetic organic chemistry. To illustrate the impact microwave assisted organic synthesis can have on chemical research, case studies drawn mainly from the pharmaceutical industry are presented.

Content:
Chapter 1 Theoretical Aspects of Microwave Dielectric Heating (pages 1–22): D. Michael P. Mingos
Chapter 2 Microwave?Acceleratedmetal Catalysis: Organic Transformations at Warp Speed (pages 23–43): Kristofer Olofsson and Mats Larhed
Chapter 3 Heterocyclic Chemistry Using Microwave?Assisted Approaches (pages 44–74): Thierry Besson and Christopher T. Brain
Chapter 4 Microwave?Assisted Reductions (pages 75–101): Timothy N. Danks and Gabriele Wagner
Chapter 5 Speed and Efficiency in the Production of Diverse Structures: Microwave?Assisted Multi?Component Reactions (pages 102–132): Jacob Westman
Chapter 6 Integrating Microwave?Assisted Synthesis and Solid?Supported Reagents (pages 133–176): Ian R. Baxendale, Dr. Ai?Lan Lee and Prof. Steven V. Ley
Chapter 7 Microwave?Assisted Solid?Phase Synthesis (pages 177–221): Alexander Stadler and C. Oliver Kappe
Chapter 8 Timesavings Associated with Microwave?Assisted Synthesis: A Quantitative Approach (pages 222–236): Christopher R. Sarko
Chapter 9